Small Intestine Lymphoma: 7 Compassionate Ways To Brave Feline Cancer

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Matisse’s Journey

When Matisse was diagnosed with small intestine lymphoma in October 2023, my world felt like it had been turned upside down, especially since I had just been down the same road with my little cuddle bug Fia. The word “cancer” can be horrifying, especially when it involves a beloved feline family member. The diagnosis came after weeks of an incredibly challenging and exhausting experience that pushed me to my emotional and physical limits. But through careful treatment and dedicated care, I’m grateful to share that Matisse is now in remission. 

1. First Signs: When Something Wasn’t Right

White cat laying on white table slightly looking at camera at vet clinic being examined by vet in white coat wearing a white face mask and stethoscope checking cat stomach for small intestine lymphoma cancer. Background has blurred window.

Our journey began with subtle changes – lower energy levels, moderate weight loss, diarrhea, and a decreased appetite. The months leading up to Matisse’s diagnosis were brutal. He was experiencing severe diarrhea daily – and I mean daily. After long workdays, coming home to constant cleanup was emotionally and physically draining. There were moments I felt completely overwhelmed, exhausted beyond measure. Cleaning up multiple diarrhea incidents after a full day of work tested every ounce of my patience and love. Some nights, I would just sit on the floor, surrounded by cleaning supplies and cat shampoo feeling totally defeated and wondering how much more I could handle.

2. The Diagnosis: Understanding Feline Lymphoma

Doctor holding green ribbon in hands in front for world Lymphoma Awareness. Doctor is wearing teal colored scrubs with a stethoscope and white wall in background.

Our veterinarian explained that these digestive issues were likely related to his underlying small intestine lymphoma. These non-specific signs are common with feline lymphoma, and I’m thankful we caught it early. After consulting with our veterinarian, we learned that small intestine lymphoma in cats has a remarkably hopeful prognosis. 

The gold standard treatment for Matisse was surprisingly manageable. We opted for oral chlorambucil chemotherapy combined with prednisolone, a treatment that could be administered at home. This approach is less aggressive than human chemotherapy, focusing on maintaining quality of life rather than pursuing an extreme cure.

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3. Treatment Options: Gentle Chemotherapy at Home

White tablet in a hand with blurred  cat silver tabby with yellow eyes in background.

What surprised me most was how well Matisse tolerated the treatment.  Remarkably, the treatment not only helped manage his cancer but also significantly improved his digestive issues. Veterinary chemotherapy is dramatically different from human experiences. The dosages are lower, and the approach is gentler. In fact, about 90% of cats experience minimal to no side effects. Matisse was one of the lucky ones – he remained playful and comfortable throughout his treatment.

4. Unexpected Relief: How Treatment Resolved Daily Struggles

Matisse in remission and looking spry. Matisse is a black and white tuxedo long haired cat with green eyes sitting on a dark wood floor next to chairs while looing at the camera.
Matisse in remission and looking spry.

Our treatment goals were clear: minimize discomfort, slow cancer progression, and most importantly, preserve Matisse’s quality of life. The medication protocol we followed typically leads to remission in 90-95% of cats with small intestine lymphoma, with an average remission duration of two years. In the beginning, we went each month, and worked closely with our veterinarian to monitor his progress and adjust treatment as needed.

5. The Remission Victory: 9 Months and Counting

Matisse, a black and white long haired tuxedo cat with green eyes sitting in center of his sky fuzzy blue with white clouds circular tunnel toy on dark wooden floor while looking forward with Isaac, a white and brown tabby standing to look out window. Red couch with gray cat blanket on it in background with black and silver air purifier and magazine rack next to couch.
Matisse playing with his tunnel toy and Isaac looking out window in background

Matisse has been in remission for about 9 months. I truly treasure every day with my little bubba boy and hope to have many more days with him. We have spurts of play time together and he’s happy…and that’s all that matters.

6. Quality of Life: Maintaining Joy Through Treatment

Young girl playing with a gray British Shorthair cat  with red wand and string on bed with beige and tan paisley print sheets and similar print and color on wall and green plants above headboard or bed in background.

For other pet owners facing a similar diagnosis, I want to offer hope. Don’t be scared by the word “chemotherapy.” In veterinary medicine, it’s a compassionate approach designed to keep your pet comfortable and happy. Always communicate openly with your veterinarian about any concerns or side effects.

Today, Matisse is thriving. He’s back to his playful self, enjoying looking out the window from one of his many beds around the house and demanding his Purina Pro Plan Hydra Care, aka “stuff” AND Gerber turkey baby food with his usual enthusiasm. The daily diarrhea is a distant memory, and our home is peaceful again. Our journey wasn’t just about treating cancer – it was about maintaining his spirit and joy, and finding strength I didn’t know I possessed.

7. Hope for Other Pet Parents: You’re Not Alone

Matisse, a black and white long haired tuxedo cat with green eyes and looking to the left side hanging over edge of apple green velvet couch and his white cat bed on top. Blurred background with black clock, wood fireplace, tv and decor hanging on walls.
Matisse with wind blown hair hanging out

To fellow pet parents facing similar challenges: stay informed, stay hopeful, and never underestimate the power of love in healing. And remember, it’s okay to feel overwhelmed – you’re not alone.

Disclaimer: Always consult with a veterinary professional for specific medical advice tailored to your pet’s individual needs.


Join the Conversation!

Have you ever faced a challenging pet health journey? I’d love to hear from you. Drop a comment below and share your story:

  • Have you or someone you know dealt with small intestine lymphoma cancer?
  • What was the most challenging aspect of caring for your sick cat?
  • How did you find strength during difficult times with your furry companion?

Your experiences and insights could provide comfort and support to other cat parents going through similar challenges. Let’s create a supportive community where we can share, learn, and uplift each other.

Author’s Note: If you found this post helpful, please share it with other cat lovers who might need hope and information. Sometimes, knowing you’re not alone can make all the difference. And don’t forget to follow my blog for more stories about life with Isaac, Matisse and Dexter and insights into our feline friends’ fascinating behaviors.

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